Research by South African government scientists reveals that mutations of the new variant, known as 501Y.v2 or B1351, make the variant substantially resistant to antibodies in blood plasma donated by Covid patients.
The findings suggest it may be more likely to reinfect people who have already had Covid, and that vaccines being rolled out across the globe may be less effective. Since the variant emerged late last year, it has prompted travel bans around the world
The researchers found that the ability of antibodies to neutralise the virus typically fell eight-fold with the new variant, meaning that in lab tests eight times as much antibody was needed to disable the B1351 variant than older ones.
In work that has yet to be peer-reviewed, the team at the National Institute for Communicable Diseases in Johannesburg found that the potency of antibody-rich plasma varied widely.
The neutralising ability of plasma from some patients fell a staggering 64-fold when tested against the new variant, while for others the ability to wipe out the new variant was unaffected. Nearly half, or 21 of 44 patients, “had no detectable neutralisation activity”, the scientists write.
from The Guardian.
The findings suggest it may be more likely to reinfect people who have already had Covid, and that vaccines being rolled out across the globe may be less effective. Since the variant emerged late last year, it has prompted travel bans around the world
The researchers found that the ability of antibodies to neutralise the virus typically fell eight-fold with the new variant, meaning that in lab tests eight times as much antibody was needed to disable the B1351 variant than older ones.
In work that has yet to be peer-reviewed, the team at the National Institute for Communicable Diseases in Johannesburg found that the potency of antibody-rich plasma varied widely.
The neutralising ability of plasma from some patients fell a staggering 64-fold when tested against the new variant, while for others the ability to wipe out the new variant was unaffected. Nearly half, or 21 of 44 patients, “had no detectable neutralisation activity”, the scientists write.
from The Guardian.