Generally speaking, creamy things melt and slide easier than powders (making creamy things easier to blend...). With that in mind, I'd avoid creamy things unless you use them sparingly & with a light touch.
If you're hardcore, there are some sealants that are pretty serious. Back in the day (erm, when I would go clubbing in New Orleans heat), I used to use this stuff called She-Laq by Benefit -- it basically seals anything on you. With that in mind, it is really hard core. It doesn't really do justice for au natural beauty. And it feels a little sticky to the touch.
For better or worse, I personally thing a bangin tan (not burn) does wonders to totally eliminate the need for make up.
I usually bring an all-in-one lipstick / blush stick, Revlon Colorstay Lash Tint (noooo racoon eyes & it lasts for like 3 days -- be cautious not to apply more than 2 coats), Revlon colorstay eyeliner (I swear by this stuff)and not really more than that.
Less is so much better -- especially when you're staggering home at 9 a.m.