☣ Coronavirus ☣

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The impact on severity of symptoms in older people having just one dose is an aspect that the mainstream media and Govt have not highlighted until today. So it's not surprising there has been worry about the Oxford one not really being good enough to allow a return to relative normality. Seeing as most people don't have the time to scrutinize every aspect of the detailed study results, even if they could understand them.

It seems this is the case for the pfizer one also, and UK are now postponing second jabs already due 3 weeks from the first one to about 12 weeks from Monday same as the Oxford one. That's after telling people already vaccinated with one dose they would get their second 3 weeks from the first.

I am at a loss as to why this revised strategy was not embarked on from the outset if the vaccines were that effective in reducing severity of symptoms. Just keeps rocking the confidence of people told one thing and then the whistle blows and the goalposts shift again. Perhaps the reality is they really don't actually know with any reasonable probability but that isn't a good strapline for confidence as far as vaccine uptake is concerned !

This Government really doesn't get how damaging changing your story can be, especially for older people.
 
I’ve booked myself in for a test tomorrow. Will update this post with the result and the symptoms i’ve got/ have had..

i was half expecting to be listing symptoms on here and for the test to come back negative as i haven’t been *as* floored as others but my smell and taste completely went the night i booked the test and unsurprisingly it’s came back fricken positive. Don’t get me wrong i’ve been ill but i thought it was a continuation of a cold I've had for a couple of weeks only on boxing day i started to get worries with the body aches, headaches, spells of breathlessness and fatigue...

happy new year?:lol:
 
i was half expecting to be listing symptoms on here and for the test to come back negative as i haven’t been *as* floored as others but my smell and taste completely went the night i booked the test and unsurprisingly it’s came back fricken positive. Don’t get me wrong i’ve been ill but i thought it was a continuation of a cold I've had for a couple of weeks only on boxing day i started to get worries with the body aches, headaches, spells of breathlessness and fatigue...

happy new year?:lol:
How you feeling? The loss of taste and smell is horrible


It's a strange illness, effects people so differently. All I'd say after my own experience is take it easy and dont push yourself. Take care
 
How you feeling? The loss of taste and smell is horrible


It's a strange illness, effects people so differently. All I'd say after my own experience is take it easy and dont push yourself. Take care

i think (hope) im over the worst of it. I do feel pretty sh1t but it just feels like cold again atm with a little difficulty breathing. The lack of taste/smell is so weird ! Thanks - hope you’re better now too
 
It makes sense to use the longer window to do single doses to as many as fast as possible, to get serious illness practically to zero. Then do a 2nd dose later in to reduce peeps chances of even getting infected at all.

However it's been really badly communicated as to why it's a good strategy and can have a bad smell to it; unless you dig into the actual research data. But how many people gonna do that?

Doesn't help the mhra press conference at times said it's based on data they have but can't talk about as it's not been published and made public yet ? way to go there, perhaps coordinate with the company to publish that additional data before hand?

Only small issue I can see is if you can still be infected, what are the chances of mutations that a) not defeated by produced antibodies b) have mutations that are viable for the virus?

Although t-cells will have a part to play, and if not immune compromised, likely to clean up while you're actively fighting off illness. (T-cells seem to have a broader coverage than antibodies if they are prepped).

Maybe the government so used to doing u-turns they don't see the problem ?
 
It makes sense to use the longer window to do single doses to as many as fast as possible, to get serious illness practically to zero. Then do a 2nd dose later in to reduce peeps chances of even getting infected at all.

However it's been really badly communicated as to why it's a good strategy and can have a bad smell to it; unless you dig into the actual research data. But how many people gonna do that?

Doesn't help the mhra press conference at times said it's based on data they have but can't talk about as it's not been published and made public yet ? way to go there, perhaps coordinate with the company to publish that additional data before hand?

Only small issue I can see is if you can still be infected, what are the chances of mutations that a) not defeated by produced antibodies b) have mutations that are viable for the virus?

Although t-cells will have a part to play, and if not immune compromised, likely to clean up while you're actively fighting off illness. (T-cells seem to have a broader coverage than antibodies if they are prepped).

Maybe the government so used to doing u-turns they don't see the problem ?
Our government are an absolute shambles! My Dad who usually hangs on every word they say has even lost all confidence in anything they come up with! In 30 odd years I’ve never seen him so critical of the powers running our country!
Me and the wife spoke a few years ago about possibly emigrating and I can honestly say if/when this shit is over it’s something we will explore, with one reason been we have zero trust or respect for the people in charge.
 
95% of deaths are people aged over 50. Once those people are vaccinated, deaths and hospitalizations will drop like a rock.

Also, while 10-30% may still be exposed, the vaccine limits the severity of the disease and should keep them out of the hospital.
Of course they will. That isn’t the point. 5% of deaths are under 50. When everyone is released into a free society, there are going to be a lot more transmissions. That 5% is going to grow. Add long Covid and other the 10-30% efficacy issue. There is no proof that vaccination reduces transmission and nothing is proven regarding the vaccines reducing levels of illness for those it doesn’t work on. I think these things will be worked on as these are early day vaccines, but it’s going to take time. This is a long way from being done for now.
 
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I can't stand that Katie Hopkins rat, and it's scary the amount of support she has now.

In her latest video she rants on about how the country has been shut down for only 388 people as that's the figure for covid deaths under 60 with no underlying health conditions.

So if your over 60 or have an underlying health condition you somehow don't matter anymore eh? ??‍♂️

She also implies that the nhs is under so much pressure because the staff keep 'pulling sickies'

Rat
 
I can't stand that Katie Hopkins rat, and it's scary the amount of support she has now.

In her latest video she rants on about how the country has been shut down for only 388 people as that's the figure for covid deaths under 60 with no underlying health conditions.

So if your over 60 or have an underlying health condition you somehow don't matter anymore eh? ??‍♂️

She also implies that the nhs is under so much pressure because the staff keep 'pulling sickies'

Rat
Can’t believe you are still listening to her mate. She is absolute poison. Horrible, horrible person.
 
I can't stand that Katie Hopkins rat, and it's scary the amount of support she has now.

In her latest video she rants on about how the country has been shut down for only 388 people as that's the figure for covid deaths under 60 with no underlying health conditions.

So if your over 60 or have an underlying health condition you somehow don't matter anymore eh? ??‍♂️

She also implies that the nhs is under so much pressure because the staff keep 'pulling sickies'

Rat
Is she the one where her own family disowned her, and said she suffers from delusions and mental illness and has for a very long time?

Mental illness is no laughing matter, but the internets giving anyone a voice and pulling in other susceptible people is really sad.

They act like a prion

 
I can't stand that Katie Hopkins rat, and it's scary the amount of support she has now.

In her latest video she rants on about how the country has been shut down for only 388 people as that's the figure for covid deaths under 60 with no underlying health conditions.

So if your over 60 or have an underlying health condition you somehow don't matter anymore eh? ??‍♂️

She also implies that the nhs is under so much pressure because the staff keep 'pulling sickies'

Rat
She is abhorrent. Made a very tenuous career out of being hateful. She's now trying to claw back some publicity and money after having to declare herself insolvent after she lost a court case where she made a false accusation.
 
That's the worrying bit
It's amazing who people will listen to when it agrees with what they want to hear, confirmation bias. Human psychology is very interesting.

I always play devil's advocate with myself and any opinions I have, if I had an opinion containing so many logical fallacies I would be questioning why I'd come to these conclusions, however some people will just find someone that agrees with them and that is enough.
 
UK - 56k cases today; but the good news is just short of 1m have had their first vax. That's pretty good going IMO - but to get out of this mess that's gonna have to be 1m/week or better in the NY.
Seems the shots are there, we just need people to administer them.
 
Of course they will. That isn’t the point. 5% of deaths are under 50. When everyone is released into a free society, there are going to be a lot more transmissions. That 5% is going to grow. Add long Covid and other the 10-30% efficacy issue. There is no proof that vaccination reduces transmission and nothing is proven regarding the vaccines reducing levels of illness for those it doesn’t work on. I think these things will be worked on as these are early day vaccines, but it’s going to take time. This is a long way from being done for now.

Well the under 50 group will be vaccinated as well, and it’s not like all restrictions will drop the moment the 50+ crowd are vaccinated.

Also, we know that asymptomatic spread is not a leading cause of transmission. And some of the data in the AZ trial point to a decent amount of neutralizing immunity. So I don’t think the vaccine is going to stop all transmission, but it’s gonna stop a lot.
 
I don't see what the issue is. The half/full subgroup was too small (and only 18-55yo) for MHRA approval. But the subgroup that was approved (evidently) was not. Why does one subgroup not fitting the criteria, but another subgroup fitting it, and therefore able to be accepted, a bad thing? A perfectly acceptable method has been found. There is nothing wrong with have a method that passes regulatory approval, people seem to be implying figures have been fudged. The figures have been released if you want to look at them, it's weird you'd take a lack of understanding the evidence as a reason to not trust medical professionals.

This was 12,000 people (6,000 in each arm) who received their second dose between 4-26 weeks after their first dose. Up until either a) the day they got the second dose or b) 12 weeks after their first dose, there had been 30 infections in the vaccine arm, and 101 in the control arm = so around 70 infections prevented by one dose of the vaccine for every 100 that occur. So 70% protection.

Data here: https://www.gov.uk/government/publications/regulatory-approval-of-covid-19-vaccine-astrazeneca

I guess my scepticism is more so based around how they messed up the trial without realising, and stumbled across a more effective method through an error. Something just doesn't' sit well with me when those running the trial make such a basic error.

Also not a fan of the sudden change of plan with the Pfizer vaccine if even Pfizer are saying they can't support prolonging the time between doses.

I'm not arguing that they're unsafe, or that I don't think people should get them. I just personally don't feel 100% confident in them at present.
 
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