I lived in Amsterdam for 3.5 years. If you are up for a laugh and want to stay in a cool hotel check out www.hoteldeharmonie.com. It belongs to a friend of mine called Tommy (from Dublin). It is an absolute nut house!!
Its a small hotel with 10 rooms situated on a canal in the heart of amsterdam.
For night clubs.....Check out "Escape" in rembrantplein or the "Mazzo" or Melkweg (Milkyway).
A little tip....dont smoke too much dope during the day or else you wont stray further than your hotel room. Dont spark up before 7pm!!
I've been the Club Escape, Its alright, I can't remember wehich one, But I sparked a Spliff in a club out there and all the locals had a go at me"That is forbidden in here"and all that LOL, I was shocked, But you can't spark up everywhere just cos it legal, We went to Grasshopper a few time, All the touristy places really, But thats what we wanted, Its one of the best Weekends I've ever had, Probabbly......No definately!!!
I fell in love with Amsterdam the first time I visited ('99) -- at that time I was just into wilding out, but after I returned I fell in love with the culture, lifestyle, and the people. I enjoyed walking along the canals at night and visiting the many wonderful restaurants (Supper Club). It's also a great city to shop. I started making friends there and they showed me around town and taught me about the history and social issues in Amsterdam. The only negative I have about Amsterdam is the horrible weather; I went in August and it was chilly, I went in Fall and it was cold, I went in Spring and it was raining.