for me it'd be a choice of 2 -
subliminal at pacha - morillo and harry homero; average line up, predicatable musically but one of the best nights on the island IMO
Meganite @ privilige - Picotto, Ben Sims, Marco Carola; Ben Sims is the major draw here
I'd probably end up at Subliminal though, that said is depends how long you're there for and what you plan to do on your second week. 1 subliminal night is enough.